Chemical reactions play a vital role in numerous industries ranging from pharmaceuticals to petrochemicals. To ensure these reactions occur efficiently and safely, specialized equipment is required. One such device is the 100L Jacketed Glass Reactor, a versatile tool widely used in laboratory and industrial settings.
Understanding Glass Reactor Vessel Types
Single layer glass reactor vessel:
Single-layer glass reactor vessel is a common laboratory reaction vessel. It is made of single-layer heat-resistant glass, which can withstand the erosion of high temperature and chemical reaction. The single-layer glass reactor vessel usually has a cylindrical shape with a wide bottom and a cover and aperture on the top, which is convenient for adding reagents and observing the reaction process. They are widely used in experimental operations such as dissolution, reaction, heating and stirring.
Double layer glass reactor vessel:
A double-layer glass reactor vessel is a reaction vessel with a two-layer glass structure. The inner layer is heat-resistant glass, which is used to carry the reactants and the reaction process; the outer layer is a heat insulation layer, which can reduce heat loss and heat radiation to the operator. Double-layer glass reactor vessel is often used in experiments that require heating reactions, which can provide better temperature control and safety.
Triple glass reactor vessel:
A triple glass reactor is similar to a double glass reactor vessel, but it adds a vacuum layer to the outer layer. This vacuum layer can effectively isolate the temperature inside and outside the reaction vessel, reducing heat conduction and loss. Triple-layer glass reactors are usually used for experiments that require high-temperature or low-temperature reactions, and have better thermal insulation properties.
Glass Reactor Vessel Components
Glass Body: The main part of a glass reaction vessel, usually made of heat-resistant glass, able to withstand chemical reactions and high temperature conditions.
Reactor Lid: The part used to cover the top of a glass reaction vessel. It usually has a caliber and a sealing device, which can ensure the sealing performance of the reactor and provide the import and export of samples or reagents.
Stirring system: A device used to stir the reactants during the reaction. Stirring systems typically consist of electric, magnetic or mechanical stirrers that facilitate mixing and homogenization of the reactants.
Condenser: A condenser is a device used to cool and condense reactant vapors. It usually consists of glass tubes or pipes to reduce the temperature of the reaction system by circulating a cooling medium such as cold water or coolant.
Heating/Cooling System: A device used to provide heating or cooling. It can be an electric heater, hot water circulator or refrigerator, etc., providing appropriate temperature control according to the needs of the experiment.
Vacuum system: A vacuum system is used to create or maintain a vacuum environment during a reaction. It usually includes components such as vacuum pumps, vacuum lines and valves, which can remove gas and moisture in the reactor, so as to realize the reaction under oxygen-free or inert atmosphere
Application Cases Of Glass Reactor Vessel:
Case 1: American Deli Pharmaceutical Co., Ltd.
One of our clients is an emerging pharmaceutical company in the United States, focusing on drug synthesis and development. They were faced with the challenge of synthesizing a complex pharmaceutical intermediate that is a key building block in the development of new drugs. However, traditional synthetic methods suffer from problems in terms of yield and purity, as well as side reactions and generation of waste products.
In order to solve this problem, the company decided to purchase our glass reactor vessel for optimal synthesis research. They chose a double wall glass reactor vessel with stirring system, heating/cooling function and vacuum system. The reaction kettle is heat-resistant and corrosion-resistant, able to withstand high temperature and the action of chemical reagents.
In the glass reactor vessel, the company’s research team conducted a series of experiments and optimizations. They adjusted the reaction temperature, reaction time, type and amount of catalyst, and other reaction conditions. Through continuous experiments and analysis, they gradually improved the synthetic route, increased the yield and purity, and reduced the occurrence of side reactions.
In the end, they successfully synthesized the target drug intermediate and made a remarkable breakthrough. Their optimized synthetic route was validated in a glass reactor vessel, ensuring the reproducibility and scalability of the reaction. This research achievement has laid a solid foundation for the company’s new drug development project and has been recognized by regulatory agencies and investors.
The application value of glass reactor vessel in drug synthesis and development. By using glass reactor vessel for optimization research, the company was able to overcome the limitations of traditional synthesis methods, improve the yield and purity of pharmaceutical intermediates, and provide important support for the development of new drugs. This success story demonstrates the key role of the glass reactor vessel as an experimental tool and its potential for use in the pharmaceutical industry.
Case 2: American Qida Chemical Co., Ltd.
A chemical research institute dedicated to the development of novel organic synthesis methods for the synthesis of high value-added compounds. In their research, they need to carry out a series of complex organic reactions, and need to control the temperature and stirring speed during the reaction process.
To achieve this, the agency used a single-layer glass reactor vessel. The reaction kettle is heat-resistant and can withstand chemical reagents under high-temperature reaction conditions. It is also equipped with an advanced stirring system, which can provide a uniform stirring effect to ensure that the reaction materials are fully mixed.
In the glass reactor vessel, the researchers successfully performed a series of organic synthesis reactions. They controlled the reaction temperature, stirring speed and reaction time to obtain the optimal yield and purity of the target compound. By conducting small-scale experiments in a glass reactor vessel, they were able to quickly evaluate the effect of different reaction conditions to determine optimal synthesis parameters.
With the deepening of research, the institution successfully developed an efficient synthetic method and synthesized multiple target compounds. Their research results were published in relevant academic journals and attracted widespread attention. In addition, they also successfully extended this synthesis method to a larger-capacity glass reactor vessel for large-scale production.
They highlighted the application value of glass reactor vessel in chemical synthesis research. By using the glass reactor vessel, researchers are able to perform precise temperature control and stirring effects, optimize the conditions of organic synthesis reactions, and thus obtain high yields and high purity compounds. This success story demonstrates the importance of the glass reactor vessel in the field of organic synthesis and its value as a research tool.